Author: Jun Wu; Dingyun Song; Zhongwen Li; Baojie Guo; Yani Xiao; Wenjing Liu; Lingmin Liang; Chunjing Feng; Tingting Gao; Zai Wang; Jianyan Wen; Shengnan Yang; Peipei Liu; Lei Wang; Yukai Wang; Liang Peng; Guihai Feng; Shiqiang Huang; Glyn Nigel Stacey; Wei Li; Yan Huo; Ronghua Jin; Qi Zhou; Liu Wang; Baoyang Hu; Huaping Dai; Jie Hao
Title: Immunity-and-Matrix-Regulatory Cells Derived from Human Embryonic Stem Cells Safely and Effectively Treat Mouse Lung Injury and Fibrosis Document date: 2020_4_16
ID: 8dpla6jt_87
Snippet: Like MSCs, the IMRCs are immunoprivileged, and can escape the immune response through their lack 579 of expression of HLA class II and their weak expression of HLA class I, thus making them valuable 580 choices for allogeneic cell therapy. Moreover, it has been reported that MSCs could release 581 immunomodulatory factors, alter the expression of surface molecules, and produce growth factors during 582 an immune response to the inflammatory cytok.....
Document: Like MSCs, the IMRCs are immunoprivileged, and can escape the immune response through their lack 579 of expression of HLA class II and their weak expression of HLA class I, thus making them valuable 580 choices for allogeneic cell therapy. Moreover, it has been reported that MSCs could release 581 immunomodulatory factors, alter the expression of surface molecules, and produce growth factors during 582 an immune response to the inflammatory cytokines produced by T cells and antigen-presenting cells 36 . 583
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