Author: Yue-qiang Fu; Yue-lin Sun; Si-wei Lu; Yang Yang; Yi Wang; Feng Xu
Title: Impact of blood analysis and immune function on the prognosis of patients with COVID-19 Document date: 2020_4_22
ID: a822exap_3
Snippet: Pulmonary infection caused by virus is often accompanied by changes in hematologic and immune test parameters. Neutrophil, lymphocyte, and lymphocyte subset counts may help clinicians assess the condition of patients with viral pneumonia. In patients with severe acute respiratory syndrome (SARS), an initial neutrophil count >7000/mL (odds ratio [OR] 6.4) and initial C-reactive protein (CRP) concentration >47.5 mg/L (OR 5.8) have been associated w.....
Document: Pulmonary infection caused by virus is often accompanied by changes in hematologic and immune test parameters. Neutrophil, lymphocyte, and lymphocyte subset counts may help clinicians assess the condition of patients with viral pneumonia. In patients with severe acute respiratory syndrome (SARS), an initial neutrophil count >7000/mL (odds ratio [OR] 6.4) and initial C-reactive protein (CRP) concentration >47.5 mg/L (OR 5.8) have been associated with fatality [2] . Leong et al. [3] found that neutropenia was associated with poor prognosis in patients with SARS, and Li et al. [4] reported that the peripheral CD4+ and CD8+ T lymphocyte absolute counts were significantly lower in these patients. Tang et al. [5] also showed that CD3+, CD4(+), and CD8(+) lymphocytes significantly decreased in the acute phase of SARS, especially in patients who died.
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