Analysis of the Productivity, Immunity, and Health Performance of Nile Tilapia (Oreochromis niloticus) Broodstock-fed Dietary Fermented Extracts Sourced from Saccharomyces cerevisiae (Hilyses): A Field Trial

Abu-Elala, Nermeen M.; Ali, Tamer El-Sayed; Ragaa, Naela M.; Ali, Sara E.; Abd-Elsalam, Reham M.; Younis, Nehal A.; Abdel-Moneam, Dalia A.; Hamdien, Aya H.; Bonato, Melina; Dawood, Mahmoud A.O.

SIMPLE SUMMARY: The low performance of Nile tilapia (Oreochromis niloticus) broodstock and high seed mortality along the spawning season are the major constraints which are directly reflected in hatchery profit. Broodstock nutrition is a key factor that can influence fish reproduction and subsequent larval quality. The objective of this study was to evaluate the effect of dietary fermented extracts sourced from Saccharomyces cerevisiae (nucleotides, β-glucans and MOS) (Hilyses(®)) on the seed production and health of Nile tilapia broodstock, as well as on seed survival and growth performance. The study was performed in the hatchery along the spawning season and continued in the laboratory to monitor the performance in fry and fingerlings. The results showed that dietary fermented yeast extracts could be used as a strategic approach to sustain tilapia production, as they improve the productivity and health of broodstock as well as seed survival and performance. ABSTRACT: The present study aimed to evaluate the effect of dietary fermented extracts sourced from Saccharomyces cerevisiae (nucleotides, β-glucans and MOS) (Hilyses(®)) on the production and health of Nile tilapia (Oreochromis niloticus) broodstock, as well as on seed survival and performance. The trial was performed in a hatchery along the spawning season and continued in the laboratory to monitor the performance in fry and fingerlings. The broodstock were divided into two groups, (C) fed a basal diet and (H) fed 0.4% Hilyses. Blood and histological parameters, antioxidant power, cortisol level and the expression of some immune-related (TLR-2, IL-1β and TNF-α) and growth-related genes (MUC-2 and IGF-1) were measured. The obtained seeds were subdivided into four treatments: (C-C) fed a basal diet, (C-H) fed 0.4% Hilyses, (H-C) fed a basal diet and (H-H) fed 0.4% Hilyses. Results revealed that the dietary inclusion of Hilyses in the broodstock increased seed production, survival, hematological parameters, and antioxidant power. Moreover, it improved the intestinal microstructure and upregulated the immune- and growth-related genes. The growth indices of fry and fingerlings were significantly increased in all Hilyses-treated groups (p < 0.05). The performance in the (H-H) group significantly surpassed those of all groups. Therefore, dietary fermented yeast could be used as a strategic solution to sustain tilapia production.