Author: Ying Liu; Yueping Liu; Bo Diao; Feifei Ren; Yue Wang; Jinya Ding; Qianchuan Huang
Title: Diagnostic Indexes of a Rapid IgG/IgM Combined Antibody Test for SARS-CoV-2 Document date: 2020_3_30
ID: hnetng0w_32
Snippet: Compared with other similar studies, one of our strengths was that we recorded detailed time of each patient from illness onset to sample collection. From the results (Table 3) , we can see that only 3 out of the 16 cases with positive PCR results in '0 -7' group were tested positive by SARA-CoV-2 IgG/IgM test kit, generating a sensitivity of just 18.8% (3/16). The time from illness onset to sample collection of these 16 patients in '0 -7' group .....
Document: Compared with other similar studies, one of our strengths was that we recorded detailed time of each patient from illness onset to sample collection. From the results (Table 3) , we can see that only 3 out of the 16 cases with positive PCR results in '0 -7' group were tested positive by SARA-CoV-2 IgG/IgM test kit, generating a sensitivity of just 18.8% (3/16). The time from illness onset to sample collection of these 16 patients in '0 -7' group was between 1 and 2 days. Patients in this group may be at the initial stage or 'window period' of SARS-CoV-2 infection, the concentration of antibodies was too low to be detected. In '8 -15' subgroup and '>= 16' subgroup, the sensitivity of IgG/IgM test kit jumped from 18.8% to 100% whereas the specificity in these two groups were relatively low, 50% and 64.3%, respectively.
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