Author: Han, Cong; Li, Qian; Ji, Haishuo; Xing, Wenping; Zhang, Limin; Zhang, Liyun
Title: Aptamers: The Powerful Molecular Tools for Virus Detection. Cord-id: tngdycx3 Document date: 2021_4_13
ID: tngdycx3
Snippet: Aptamers are short single-stranded DNA or RNA oligonucleotides selected by the technique of systematic evolution of ligands by exponential enrichment (SELEX). Aptamers have been demonstrated to bind various targets from small-molecule to cells or even tissues in the way of antibodies. Thus they are called chemical antibodies. We summarize and evaluate recent developments in aptamer-based sensors(for short aptasensors) for virus detection in this review. These aptasensors are mainly classified in
Document: Aptamers are short single-stranded DNA or RNA oligonucleotides selected by the technique of systematic evolution of ligands by exponential enrichment (SELEX). Aptamers have been demonstrated to bind various targets from small-molecule to cells or even tissues in the way of antibodies. Thus they are called chemical antibodies. We summarize and evaluate recent developments in aptamer-based sensors(for short aptasensors) for virus detection in this review. These aptasensors are mainly classified into optical and electronic aptasensors based on the type of transducer. Nowadays, the smartphone has become the most widely used mobile device with billions of users worldwide. Under the background of the ongoing COVID-19 outbreak, smartphone-based aptasensors for a portable and point-of-care test (POCT) of COVID-19 detection will be of great concern in the future.
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