Selected article for: "available data and death risk"
Author: Malcangi, Giuseppina; Inchingolo, Alessio Danilo; Inchingolo, Angelo Michele; Santacroce, Luigi; Marinelli, Grazia; Mancini, Antonio; Vimercati, Luigi; Maggiore, Maria Elena; D’Oria, Maria Teresa; Hazballa, Denisa; Bordea, Ioana Roxana; Xhajanka, Edit; Scarano, Antonio; Farronato, Marco; Tartaglia, Gianluca Martino; Giovanniello, Delia; Nucci, Ludovica; Serpico, Rosario; Sammartino, Gilberto; Capozzi, Loredana; Parisi, Antonio; Di Domenico, Marina; Lorusso, Felice; Contaldo, Maria; Inchingolo, Francesco; Dipalma, Gianna
Title: COVID-19 Infection in Children, Infants and Pregnant Subjects: An Overview of Recent Insights and Therapies
  • Cord-id: fiqyzoyq
  • Document date: 2021_9_16
    • ID: fiqyzoyq
    Snippet: Background: The SARS-CoV-2 pandemic has involved a severe increase of cases worldwide in a wide range of populations. The aim of the present investigation was to evaluate recent insights about COVID-19 infection in children, infants and pregnant subjects. Methods: a literature overview was performed including clinical trials, in vitro studies, reviews and published guidelines regarding the present paper topic. A descriptive synthesis was performed to evaluate recent insights and the effectivenes
    Document: Background: The SARS-CoV-2 pandemic has involved a severe increase of cases worldwide in a wide range of populations. The aim of the present investigation was to evaluate recent insights about COVID-19 infection in children, infants and pregnant subjects. Methods: a literature overview was performed including clinical trials, in vitro studies, reviews and published guidelines regarding the present paper topic. A descriptive synthesis was performed to evaluate recent insights and the effectiveness of therapies for SARS-CoV-2 infection in children, infants and pregnant subjects. Results: Insufficient data are available regarding the relationship between COVID-19 and the clinical risk of spontaneous abortion and premature foetus death. A decrease in the incidence of COVID-19 could be correlated to a minor expression of ACE2 in childrens’ lungs. At present, a modulation of the dose-effect posology for children and infants is necessary. Conclusions: Pregnant vertical transmission has been hypothesised for SARS-CoV-2 infection. Vaccines are necessary to achieve mass immunity for children and also pregnant subjects.

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