Author: Yichun Cheng; Ran Luo; Kun Wang; Meng Zhang; Zhixiang Wang; Lei Dong; Junhua Li; Ying Yao; Shuwang Ge; Gang Xu
Title: Kidney impairment is associated with in-hospital death of COVID-19 patients Document date: 2020_2_20
ID: ahxnhutv_4
Snippet: Although diffuse alveolar damage and acute respiratory failure were the main features of COVID-19 4 , the involvement of other organs need to be considered. After lung infection, the infiltrated virus may enter the blood circulation, accumulate in kidney and cause damage to renal resident cells. Indeed, RNAaemia, defined as a positive result for real-time PCR in the plasma sample, was found in 15% COVID-19 patients 4 . It is reported that 6.7% pa.....
Document: Although diffuse alveolar damage and acute respiratory failure were the main features of COVID-19 4 , the involvement of other organs need to be considered. After lung infection, the infiltrated virus may enter the blood circulation, accumulate in kidney and cause damage to renal resident cells. Indeed, RNAaemia, defined as a positive result for real-time PCR in the plasma sample, was found in 15% COVID-19 patients 4 . It is reported that 6.7% patients with severe acute respiratory syndrome (SARS) in 2003 developed acute renal impairment and the mortality of SARS patients with acute kidney injury (AKI) was 91.7% 5 . Thus, the kidney impairment and outcome in patients infected by SARS-CoV-2, which resembles SARS in 2003, were urgently warranted.
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