Author: Fung, Monica; Chiu, Charles Y.; DeVoe, Catherine; Doernberg, Sarah B.; Schwartz, Brian S.; Langelier, Charles; Henrich, Timothy J.; Yokoe, Deborah; Davis, John; Hays, Steven R.; Chandran, Sindhu; Kukreja, Jasleen; Ng, Dianna; Prostko, John; Taylor, Russell; Reyes, Kevin; Bainbridge, Emma; Bond, Allison; Chinâ€Hong, Peter; Babik, Jennifer M.
Title: Clinical Outcomes and Serologic Response in Solid Organ Transplant Recipients with COVIDâ€19: A Case Series from the United States Cord-id: fqkkpqph Document date: 2020_6_1
ID: fqkkpqph
Snippet: The coronavirus disease 2019 (COVIDâ€19) pandemic caused by SARS coronavirus 2 (SARSâ€CoVâ€2) has caused significant morbidity and mortality for patients and stressed healthcare systems worldwide. The clinical features, disease course, and serologic response of COVIDâ€19 among immunosuppressed patients such as solid organ transplant (SOT) recipients, who are at presumed risk for more severe disease, are not well characterized. We describe our institutional experience with COVIDâ€19 among te
Document: The coronavirus disease 2019 (COVIDâ€19) pandemic caused by SARS coronavirus 2 (SARSâ€CoVâ€2) has caused significant morbidity and mortality for patients and stressed healthcare systems worldwide. The clinical features, disease course, and serologic response of COVIDâ€19 among immunosuppressed patients such as solid organ transplant (SOT) recipients, who are at presumed risk for more severe disease, are not well characterized. We describe our institutional experience with COVIDâ€19 among ten SOT patients, including the clinical presentation, treatment modalities, and outcomes of seven renal transplant recipients, one liver transplant recipient, one heart transplant recipient, and one lung transplant recipient. In addition, we report the serologic response in SOT recipients, documenting a positive IgG response in all seven hospitalized patients. We also review the existing literature on COVIDâ€19 in SOT recipients to consolidate the current knowledge on COVIDâ€19 in the SOT population for the transplant community.
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