Collaborative Unsupervised Domain Adaptation for Medical Image Diagnosis

Zhang, Yifan; Wei, Ying; Wu, Qingyao; Zhao, Peilin; Niu, Shuaicheng; Huang, Junzhou; Tan, Mingkui

Deep learning based medical image diagnosis has shown great potential in clinical medicine. However, it often suffers two major difficulties in real-world applications: 1) only limited labels are available for model training, due to expensive annotation costs over medical images; 2) labeled images may contain considerable label noise (e.g., mislabeling labels) due to diagnostic difficulties of diseases. To address these, we seek to exploit rich labeled data from relevant domains to help the learning in the target task via {Unsupervised Domain Adaptation} (UDA). Unlike most UDA methods that rely on clean labeled data or assume samples are equally transferable, we innovatively propose a Collaborative Unsupervised Domain Adaptation algorithm, which conducts transferability-aware adaptation and conquers label noise in a collaborative way. We theoretically analyze the generalization performance of the proposed method, and also empirically evaluate it on both medical and general images. Promising experimental results demonstrate the superiority and generalization of the proposed method.