Author: Gabriel A Brat; Griffin M Weber; Nils Gehlenborg; Paul Avillach; Nathan P Palmer; Luca Chiovato; James Cimino; Lemuel R Waitman; Gilbert S Omenn; Alberto Malovini; Jason H Moore; Brett K Beaulieu-Jones; Valentina Tibollo; Shawn N Murphy; Sehi L'Yi; Mark S Keller; Riccardo Bellazzi; David A Hanauer; Arnaud Serret-Larmande; Alba Gutierrez-Sacristan; John J Holmes; Douglas S Bell; Kenneth D Mandl; Robert W Follett; Jeffrey G Klann; Douglas A Murad; Luigia Scudeller; Mauro Bucalo; Katie Kirchoff; Jean Craig; Jihad Obeid; Vianney Jouhet; Romain Griffier; Sebastien Cossin; Bertrand Moal; Lav P Patel; Antonio Bellasi; Hans U Prokosch; Detlef Kraska; Piotr Sliz; Amelia LM Tan; Kee Yuan Ngiam; Alberto Zambelli; Danielle L Mowery; Emily Schiver; Batsal Devkota; Robert L Bradford; Mohamad Daniar; Christel Daniel; Vincent Benoit; Romain Bey; Nicolas Paris; Patricia Serre; Nina Orlova; Julien Dubiel; Martin Hilka; Anne Sophie Jannot; Stephane Breant; Judith Leblanc; Nicolas Griffon; Anita Burgun; Melodie Bernaux; Arnaud Sandrin; Elisa Salamanca; Thomas Ganslandt; Tobias Gradinger; Julien Champ; Martin Boeker; Patricia Martel; Alexandre Gramfort; Olivier Grisel; Damien Leprovost; Thomas Moreau; Gael Varoquaux; Jill Jen Vie; Demian Wassermann; Arthur Mensch; Charlotte Caucheteux; Christian Haverkamp; Guillaume Lemaitre; Christian Haverkamp; Tianxi Cai; Isaac S Kohane
Title: International Electronic Health Record-Derived COVID-19 Clinical Course Profile: The 4CE Consortium Document date: 2020_4_18
ID: 4y5279c5_60
Snippet: In addition, data alignment by a metric that indicates clinical status is necessary to better establish outcomes. Using day of diagnosis as an alignment strategy did not allow for clear identification of causes for temporal patterns. Similarly, outcomes need to be selected that represent clinically meaningful endpoints secondary to this initial data alignment. One reason for this difficulty was that identification of level of care was not easily .....
Document: In addition, data alignment by a metric that indicates clinical status is necessary to better establish outcomes. Using day of diagnosis as an alignment strategy did not allow for clear identification of causes for temporal patterns. Similarly, outcomes need to be selected that represent clinically meaningful endpoints secondary to this initial data alignment. One reason for this difficulty was that identification of level of care was not easily performed. Accordingly, it was not easy to follow patients in and out of ICUs at the site level and ICU data was not reliable.
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