Author: Carla Mavian; Simone Marini; Mattia Prosperi; Marco Salemi
Title: A snapshot of SARS-CoV-2 genome availability up to 30th March, 2020 and its implications Document date: 2020_4_5
ID: 8vl0okiv_1
Snippet: In December 2019, a novel coronavirus, SARS-CoV-2, was identified in Wuhan, China, as the etiologic agent of coronavirus disease 2019 , which by March 2020 has already spread across more than 80 countries (1) . Common symptoms of infection include fever, cough, and shortness of breath, while severe cases are characterized by advanced respiratory distress and pneumonia, often resulting in death (2) . It is still unknown what proportion of infected.....
Document: In December 2019, a novel coronavirus, SARS-CoV-2, was identified in Wuhan, China, as the etiologic agent of coronavirus disease 2019 , which by March 2020 has already spread across more than 80 countries (1) . Common symptoms of infection include fever, cough, and shortness of breath, while severe cases are characterized by advanced respiratory distress and pneumonia, often resulting in death (2) . It is still unknown what proportion of infected people that only present mild or no symptoms are spreading the virus. A recent study showed that in Wuhan whom roughly 60% of all infections were spread by asymptomatic subjects (3) . This characteristic significantly thwarts the job of public health officials who are trying to detect transmission clusters. Few transmission clusters have been identified in China recently through epidemiological contact tracing. However, because of the ongoing nature of the outbreak, it is even more complicated if not impossible to detect transmission clusters using genetic data.
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