Selected article for: "APACHE II score and ctni bnp ast"
Author: Yi Han; Haidong Zhang; Sucheng Mu; Wei Wei; Chaoyuan Jin; Yuan Xue; Chaoyang Tong; Yunfei Zha; Zhenju Song; Guorong Gu
Title: Lactate dehydrogenase, a Risk Factor of Severe COVID-19 Patients
  • Document date: 2020_3_27
    • ID: 54o2p36a_7
    Snippet: We used clinical severity scores (APACHE II and SOFA) to assess the disease severity in COVID-19 patients. The average APACHE II score was 9.9 in severe cases versus 4.7 in non-severe cases, with SOFA score of 3.0 versus 1.0 (Table 1 , P < 0.001). For the predivtive factors we have speculated, lymphocyte cell counts, hepatic function indicator AST, infection indicator CRP and myocardial injury biomarkers cTnI, BNP as well as LDH were performed Pe.....
    Document: We used clinical severity scores (APACHE II and SOFA) to assess the disease severity in COVID-19 patients. The average APACHE II score was 9.9 in severe cases versus 4.7 in non-severe cases, with SOFA score of 3.0 versus 1.0 (Table 1 , P < 0.001). For the predivtive factors we have speculated, lymphocyte cell counts, hepatic function indicator AST, infection indicator CRP and myocardial injury biomarkers cTnI, BNP as well as LDH were performed Pearson correlation ananalysis with APACHE II score and SOFA score. We found that serum LDH level showed tightly positive correlation of the highest R value respevtively with APACHE II (R = 0.682, P < 0.001) and SOFA score (R = 0.790, P < 0.001) in all the indicators (Figure1. F&L). Apart from lymphocyte cells showed a negative correlation with APACHE II (R = -0.593, P < 0.001) and SOFA score (R = -0.614, P < 0.001), other indicators CRP, AST and BNP were also positively associated with the scores. It's worth noting that, the serum cTnI level showed a positive correlation with SOFA score (R = 0.345, P = 0.025) while it showed no correlation with APACHE II score (R = 0.292, P = 0.06). (Figure 1 ).

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