Author: Brault, Clément; Zerbib, Yoann; Kontar, Loay; Carpentier, Mathieu; Maizel, Julien; Slama, Michel
Title: Positive end-expiratory pressure in COVID-19-related ARDS: Do not forget the airway closure Cord-id: e7hq39yg Document date: 2021_4_20
ID: e7hq39yg
Snippet: Airway closure is a physiological phenomenon in which the distal airways are obstructed when the airway pressure drops below the airway opening pressure. We assessed this phenomenon in 27 patients with coronavirus disease 2019-related acute respiratory distress syndrome. Twelve (44%) patients had an airway opening pressure above 5 cmH(2)O. The median airway opening pressure was 8 cmH(2)O (interquartile range, 7–10), with a maximum value of 17 cmH(2)O. Three patients had a baseline positive end
Document: Airway closure is a physiological phenomenon in which the distal airways are obstructed when the airway pressure drops below the airway opening pressure. We assessed this phenomenon in 27 patients with coronavirus disease 2019-related acute respiratory distress syndrome. Twelve (44%) patients had an airway opening pressure above 5 cmH(2)O. The median airway opening pressure was 8 cmH(2)O (interquartile range, 7–10), with a maximum value of 17 cmH(2)O. Three patients had a baseline positive end-expiratory pressure lower than the airway opening pressure.
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