Selected article for: "mean time and treatment time"

Author: Kenneth Lyon; Luis U. Aguilera; Tatsuya Morisaki; Brian Munsky; Timothy J. Stasevich
Title: Live-cell single RNA imaging reveals bursts of translational frameshifting
  • Document date: 2018_11_24
  • ID: 4fm1skgh_120
    Snippet: The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. . https://doi.org/10.1101/478040 doi: bioRxiv preprint intensity of all translation sites in each frame (and in all cells) were then totaled to produce the run-off curve. Run-off curves were normalized to the mean of the total intensity of the first four time points after treatment of harringtonine began. These curves were then fit to a linear regression to.....
    Document: The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. . https://doi.org/10.1101/478040 doi: bioRxiv preprint intensity of all translation sites in each frame (and in all cells) were then totaled to produce the run-off curve. Run-off curves were normalized to the mean of the total intensity of the first four time points after treatment of harringtonine began. These curves were then fit to a linear regression to estimate run-off times (see Fig. S7 ). The linear portion of the runoff decay begins when the normalized run-off intensity reaches a fraction 0 , where

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