Author: Natalia B. Hubbs; Mareena M. Whisby-Pitts; Jonathan L. McMurry
Title: Kinetic Analysis of Bacteriophage Sf6 Binding to Outer Membrane Protein A Using Whole Virions Document date: 2019_1_2
ID: ktds6nla_33
Snippet: The data presented herein suggest that the previously reported differences in Sf6 infection efficiencies seen in vivo and the differences in Sf6 genome ejection efficiencies in vitro [23] are not based solely on the kinetics of receptor binding. There are no significant kinetic differences between Sf6 binding to the various OmpA-TMs, nor are there any significant changes when temperature is varied, even though both factors have been shown to caus.....
Document: The data presented herein suggest that the previously reported differences in Sf6 infection efficiencies seen in vivo and the differences in Sf6 genome ejection efficiencies in vitro [23] are not based solely on the kinetics of receptor binding. There are no significant kinetic differences between Sf6 binding to the various OmpA-TMs, nor are there any significant changes when temperature is varied, even though both factors have been shown to cause changes in infection efficiency. Our results are similar to those in another study in which the authors use SPR and demonstrate that amino acid substitutions in the coronavirus receptor binding protein do not greatly affect the overall kinetic parameters when binding to the human receptor CD26 [35] .
Search related documents:
Co phrase search for related documents- acid substitution and coronavirus receptor: 1, 2, 3, 4
- acid substitution and human receptor: 1, 2, 3, 4, 5, 6, 7
- acid substitution and receptor binding: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- bind protein and coronavirus receptor: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14
- bind protein and human receptor: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- bind protein and receptor binding: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- coronavirus receptor and human receptor: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- coronavirus receptor and infection efficiency: 1, 2, 3
- coronavirus receptor and receptor binding: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- human receptor and infection efficiency: 1, 2, 3, 4
- human receptor and receptor binding: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- infection efficiency and receptor binding: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13
- previously report and receptor binding: 1, 2
Co phrase search for related documents, hyperlinks ordered by date