Development features of coronavirus disease complications in patients with coronary heart disease

Nurillaeva, N. M.; Makhkamova, M. M.; Omarov, K. B.

Background and Aims: To study the incidence and clinical features of myocardial infarction development in patients with coronary heart disease (CHD) after suffering coronavirus disease. Methods: We studied clinical condition of 64 patients admitted with chest pain complaints to the emergency room of the multidisciplinary clinic of the Tashkent Medical Academy. The average age was 52,5±2,4 years. Results: Only 41 patients (64%) had acute myocardial infarction (MI) with various localization. The group included 10 women and 31 men. The pain verbal scale showed a low level of pain syndrome, as well as an atypical location of pain in the heart. In 13 patients, was detected a high level of IgG of coronavirus infection, whereas IgM level was high in 28 patients. The level of fibrinogen in the blood plasma averaged 355 g/l, the blood sugar level was around 7.3 mmol/l on an empty stomach, hematocrit level increased to approximately 0.49 l/l. In men, was noted the decrease of blood hemoglobin to 101.6 g/l. The rest of the indicators were practically not deviated from the norm. The ECG shows typical elevations of the ST segment from the isoline. Conclusions: Atypical clinical development signs of MI in patients with CHD is associated with a previous coronavirus infection, a large amount of lung tissue damage, a low awareness of patients about possible complications of CHD and low adherence to maintenance drug therapy after suffering Covid-19.