Author: Mietto, Cristina; Salice, Valentina; Ferraris, Matteo; Zuccon, Gianmarco; Valdambrini, Federico; Piazzalunga, Giorgio; Socrate, Anna Maria; Radrizzani, Danilo
Title: Acute lower limb ischemia as clinical presentation of COVID-19 infection Cord-id: t8ynd1ew Document date: 2020_8_11
ID: t8ynd1ew
Snippet: Novel 2019 coronavirus (COVID-19) infection usually causes a respiratory disease, that may vary in severity from mild symptoms to severe pneumonia with multiple organ failure. Coagulation abnormalities are frequent, and reports suggest that COVID-19 may predispose to venous and arterial thrombotic complications. We report a case of acute lower limb ischemia and resistance to heparin as the onset of COVID-19 disease, preceding the development of respiratory failure. This case highlights that the
Document: Novel 2019 coronavirus (COVID-19) infection usually causes a respiratory disease, that may vary in severity from mild symptoms to severe pneumonia with multiple organ failure. Coagulation abnormalities are frequent, and reports suggest that COVID-19 may predispose to venous and arterial thrombotic complications. We report a case of acute lower limb ischemia and resistance to heparin as the onset of COVID-19 disease, preceding the development of respiratory failure. This case highlights that the shift of coagulation profile towards hypercoagulability was associated with the acute ischemic event and influenced the therapy.
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