Author: Chin-Yi Chu; Xing Qiu; Matthew N. McCall; Lu Wang; Anthony Corbett; Jeanne Holden-Wiltse; Christopher Slaunwhite; Qian Wang; Christopher Anderson; Alex Grier; Steven R. Gill; Gloria S. Pryhuber; Ann R. Falsey; David J. Topham; Mary T. Caserta; Edward E. Walsh; Thomas J Mariani
Title: Insufficiency in airway interferon activation defines clinical severity to infant RSV infection Document date: 2019_5_20
ID: bx49tbui_61
Snippet: Transcriptome analysis of airway samples collected from subjects during the acute phase of their RSV infection included the assessment of 13,688 genes following standard QC-based sample and gene filtering 28, 35 . As we previously described, gene expression data from this procedure is enriched in canonical (e.g., CDH1, EPCAM) and upper airway-specific (e.g., BPIFs, MUCs) marker genes, with lower levels of expression for leukocyte markers (Supplem.....
Document: Transcriptome analysis of airway samples collected from subjects during the acute phase of their RSV infection included the assessment of 13,688 genes following standard QC-based sample and gene filtering 28, 35 . As we previously described, gene expression data from this procedure is enriched in canonical (e.g., CDH1, EPCAM) and upper airway-specific (e.g., BPIFs, MUCs) marker genes, with lower levels of expression for leukocyte markers (Supplemental Figure 2) . We initially explored the relationship between gene expression and demographic variables. Univariate analysis indicated that All rights reserved. No reuse allowed without permission.
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