Author: Kenneth Lyon; Luis U. Aguilera; Tatsuya Morisaki; Brian Munsky; Timothy J. Stasevich
Title: Live-cell single RNA imaging reveals bursts of translational frameshifting Document date: 2018_11_24
ID: 4fm1skgh_43
Snippet: (i) frameshifted proteins originate from a small subset of RNA that frameshift with high efficiency; (ii) frameshifting occurs preferentially in multi-RNA translation factories that are facilitated in part by the frameshift sequence; (iii) frameshifting occurs in bursts on single RNA that can last for several rounds of translation; (iv) ribosomes that frameshift are paused for longer at the frameshifting sequence than ribosomes that do not frames.....
Document: (i) frameshifted proteins originate from a small subset of RNA that frameshift with high efficiency; (ii) frameshifting occurs preferentially in multi-RNA translation factories that are facilitated in part by the frameshift sequence; (iii) frameshifting occurs in bursts on single RNA that can last for several rounds of translation; (iv) ribosomes that frameshift are paused for longer at the frameshifting sequence than ribosomes that do not frameshift;
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