Author: Jing Liu; Sumeng Li; Jia Liu; Boyun Liang; Xiaobei Wang; Hua Wang; Wei Li; Qiaoxia Tong; Jianhua Yi; Lei Zhao; Lijuan Xiong; Chunxia Guo; Jin Tian; Jinzhuo Luo; Jinghong Yao; Ran Pang; Hui Shen; Cheng Peng; Ting Liu; Qian Zhang; Jun Wu; Ling Xu; Sihong Lu; Baoju Wang; Zhihong Weng; Chunrong Han; Huabing Zhu; Ruxia Zhou; Helong Zhou; Xiliu Chen; Pian Ye; Bin Zhu; Shengsong He; Yongwen He; Shenghua Jie; Ping Wei; Jianao Zhang; Yinping Lu; Weixian Wang; Li Zhang; Ling Li; Fengqin Zhou; Jun Wang; Ulf Dittmer; Mengji Lu; Yu Hu; Dongliang Yang; Xin Zheng
Title: Longitudinal characteristics of lymphocyte responses and cytokine profiles in the peripheral blood of SARS-CoV-2 infected patients Document date: 2020_2_18
ID: 9xmeyrtu_13
Snippet: In order to further determine the kinetic changes of different lymphocyte subsets in the peripheral blood of COVID-19 patients, we performed flow cytometry to stain CD3 + T cells, CD4 + and CD8 + T cell subsets, B cells and NK cells. Similar to the findings for lymphocytes, sustained decreases in CD3, CD8 and CD4 T cell counts was observed in the severe group compared to those of the mild patients during clinical observation ( The differences in .....
Document: In order to further determine the kinetic changes of different lymphocyte subsets in the peripheral blood of COVID-19 patients, we performed flow cytometry to stain CD3 + T cells, CD4 + and CD8 + T cell subsets, B cells and NK cells. Similar to the findings for lymphocytes, sustained decreases in CD3, CD8 and CD4 T cell counts was observed in the severe group compared to those of the mild patients during clinical observation ( The differences in CD3 and CD8 T cell counts between the two groups were significant at the time points of disease onset and 7-9 days later (Figure 2A and 2C).
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