Author: Hassaan Ahmed; Kajal Patel; Darren Greenwood; Stephen Halpin; Penny Lewthwaite; Abayomi Salawu; Lorna Eyre; Andrew Breen; Rory O'Connor; Anthony Jones; Manoj Sivan
Title: LONG-TERM CLINICAL OUTCOMES IN SURVIVORS OF CORONAVIRUS OUTBREAKS AFTER HOSPITALISATION OR ICU ADMISSION: A SYSTEMATIC REVIEW AND META-ANALYSIS OF FOLLOW-UP STUDIES Document date: 2020_4_22
ID: bzc7luwj_16
Snippet: The long-term complications of coronavirus infection are not well understood. The prevalence, severity and prognosis of these complications must be determined to plan the rehabilitation of survivors of the current COVID-19 pandemic. This systematic review collates these long-term complications seen following previous coronavirus outbreaks (SARS and MERS) in those who required hospitalisation or ICU stay. Our findings highlighted that the health-r.....
Document: The long-term complications of coronavirus infection are not well understood. The prevalence, severity and prognosis of these complications must be determined to plan the rehabilitation of survivors of the current COVID-19 pandemic. This systematic review collates these long-term complications seen following previous coronavirus outbreaks (SARS and MERS) in those who required hospitalisation or ICU stay. Our findings highlighted that the health-related quality of life (HRQoL), measured using SF-36, is considerably reduced in CoV survivors at 6 months postinfection, shows only slight improvement beyond 6 months and remains below normal population and those with chronic conditions [ Figure 9 ]. As these SF-36 scores reflect impairment in physical, mental and social functioning of well-being, it is not surprising that the key areas of impairments identified in our systematic review were pulmonary dysfunction, reduced exercise tolerance and psychological problems.
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