Author: Levi, Marcel; Hunt, Beverley J.
Title: Thrombosis and coagulopathy in COVIDâ€19: An illustrated review Cord-id: gm0qhfjt Document date: 2020_7_11
ID: gm0qhfjt
Snippet: This illustrated review discusses the haemostatic changes seen in patients with severe coronavirus disease 2019 (COVIDâ€19) infection and their possible causes. We discuss the crosstalk between inflammation and coagulation resulting in high levels of acuteâ€phase proteins, very high levels of Dâ€dimers, and absence of disseminated intravascular coagulation seen in patients with severe COVIDâ€19. There appear to be high rates of venous thromboembolism and also, what has been poorly described
Document: This illustrated review discusses the haemostatic changes seen in patients with severe coronavirus disease 2019 (COVIDâ€19) infection and their possible causes. We discuss the crosstalk between inflammation and coagulation resulting in high levels of acuteâ€phase proteins, very high levels of Dâ€dimers, and absence of disseminated intravascular coagulation seen in patients with severe COVIDâ€19. There appear to be high rates of venous thromboembolism and also, what has been poorly described before in acute lung injury, a high rate of pulmonary immunothrombosis (thrombosis secondary to inflammation).
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