Author: Francisca Verdugo-Paiva; Ariel Izcovich; Martin Ragusa; Gabriel Rada
Title: Lopinavir/ritonavir f?or the treatment of COVID-19: A living systematic review protocol Document date: 2020_4_17
ID: mhi6w4mr_30
Snippet: The intervention of interest is the combination of lopinavir/ritonavir. We will not restrict our criteria to any dosage, duration, timing or route of administration. The comparison of interest will be placebo (lopinavir/ritonavir plus optimal treatment versus placebo plus optimal treatment) or no treatment (lopinavir/ritonavir plus optimal treatment versus optimal treatment). Trials assessing lopinavir/ritonavir plus other drugs will be eligible .....
Document: The intervention of interest is the combination of lopinavir/ritonavir. We will not restrict our criteria to any dosage, duration, timing or route of administration. The comparison of interest will be placebo (lopinavir/ritonavir plus optimal treatment versus placebo plus optimal treatment) or no treatment (lopinavir/ritonavir plus optimal treatment versus optimal treatment). Trials assessing lopinavir/ritonavir plus other drugs will be eligible if the cointerventions are identical in both intervention and comparison groups. Trials evaluating lopinavir/ritonavir in combination with other active drugs versus placebo or no treatment will be also included.
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