Selected article for: "gene expression and NF κB signaling blockade"
Author: Andrew J. McNamara; Pranav Danthi
Title: Loss of IKK subunits limits NF-?B signaling in reovirus infected cells
  • Document date: 2019_11_15
    • ID: e13xm0mh_8
    Snippet: We show here that reovirus infection inhibits NF-κB signaling ( Fig. 1, 2 The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. It . https://doi.org/10.1101/843680 doi: bioRxiv preprint 14 blockade of NF-κB (Fig. 5) . Thus, detection of viral RNA activates NF-κB early in 247 infection and expression of one or more viral gene products following establishment of 248 infection results in blockade NF-κB, limit.....
    Document: We show here that reovirus infection inhibits NF-κB signaling ( Fig. 1, 2 The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. It . https://doi.org/10.1101/843680 doi: bioRxiv preprint 14 blockade of NF-κB (Fig. 5) . Thus, detection of viral RNA activates NF-κB early in 247 infection and expression of one or more viral gene products following establishment of 248 infection results in blockade NF-κB, limiting further signaling through this pathway. 249

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