Author: Marino, Dario; Finotto, Silvia; Basso, Umberto; Galiano, Antonella; Bolshinsky, Maital; Amato, Ottavia; Marson, Piero; Tison, Tiziana; Colpo, Anna; Zagonel, Vittorina
                    Title: To Transplant or Not to Transplant During the SARSâ€CoVâ€2 Pandemic? That Is the Question  Cord-id: grxrtv0u  Document date: 2020_10_23
                    ID: grxrtv0u
                    
                    Snippet: The novel coronavirus disease 2019 has grown to be a global public health emergency. The rapid spread of the infection has raised many questions in the oncohematological scientific community regarding the appropriateness of highâ€dose chemotherapy with autologous stem cell transplantation (ASCT). We here report two cases of patients who received ASCT at our Institute during the epidemic in Italy, affected with Hodgkin lymphoma and germ cell tumor, respectively. The two patients underwent a naso
                    
                    
                    
                     
                    
                    
                    
                    
                        
                            
                                Document: The novel coronavirus disease 2019 has grown to be a global public health emergency. The rapid spread of the infection has raised many questions in the oncohematological scientific community regarding the appropriateness of highâ€dose chemotherapy with autologous stem cell transplantation (ASCT). We here report two cases of patients who received ASCT at our Institute during the epidemic in Italy, affected with Hodgkin lymphoma and germ cell tumor, respectively. The two patients underwent a nasopharyngeal swab for severe acute respiratory syndrome coronavirus 2 (SARSâ€CoVâ€2) on hospital admittance and during the period of bone marrow aplasia. They were attended to exclusively by dedicated health care staff who followed specifically implemented protocols for bedside nursing and care. They completed the procedure without unexpected side effect. Our experience demonstrates how ASCT can be performed safely if procedures are reorganized ad hoc to reduce the risk of SARSâ€CoVâ€2 infection.
 
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