Author: James T. VanLeuven; Benjamin J. Ridenhour; Craig R. Miller; Tanya A. Miura
Title: Lung epithelial cells have virus-specific and shared gene expression responses to infection by diverse respiratory viruses Document date: 2016_12_2
ID: iedh762s_19
Snippet: At 24 h, when gene expression changes were the highest, genes that were up-regulated by MHV infection had 134 log2-fold change values of less than five. In contrast, PR8 and RV induced expression of many genes by 135 greater than five log2-fold at 24 h, and genes were spread consistently across the full range of values. By 24 h, 136 the genes most strongly up-regulated by PR8 and RV induced changes of 7 -9.5 log2-fold and 6 -7.5 log2-137 fold com.....
Document: At 24 h, when gene expression changes were the highest, genes that were up-regulated by MHV infection had 134 log2-fold change values of less than five. In contrast, PR8 and RV induced expression of many genes by 135 greater than five log2-fold at 24 h, and genes were spread consistently across the full range of values. By 24 h, 136 the genes most strongly up-regulated by PR8 and RV induced changes of 7 -9.5 log2-fold and 6 -7.5 log2-137 fold compared to mock, respectively. This same pattern was observed with the down-regulated genes ( Figure 138 1).
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