Selected article for: "main analysis and sensitivity analysis"
Author: Bingyi Yang; Justin Lessler; Huachen Zhu; Chaoqiang Jiang; Jonathan M. Read; James A Hay; Kin On Kwok; Ruiyin Shen; Yi Guan; Steven Riley; Derek A.T. Cummings
Title: Life course exposures continually shape antibody profile and risk of seroconversion to influenza
  • Document date: 2020_1_16
    • ID: cyxn7dpw_117
    Snippet: We assumed a linear effect of age on seroconversion to recent strains in the main analysis, and performed sensitivity analysis by assuming a non-linear effect of age. We fitted GAM with seroconversion to recent strains adjusted for age in a spline form, titer to strain i, titer to strain i-1 and the summary metrics. We found consistent patterns in the association between age and seroconversion after adjusting for other covariates, however, these .....
    Document: We assumed a linear effect of age on seroconversion to recent strains in the main analysis, and performed sensitivity analysis by assuming a non-linear effect of age. We fitted GAM with seroconversion to recent strains adjusted for age in a spline form, titer to strain i, titer to strain i-1 and the summary metrics. We found consistent patterns in the association between age and seroconversion after adjusting for other covariates, however, these associations were not significant ( fig. S9 ) and did not affect our main outcome (table S7) .

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