Author: Dannielle Wellington; Zixi Yin; Liwei Zhang; Jessica Forbester; Kerry Kite; Henry Laurenson-Schafer; Shokouh Makvandi-Nejad; Boquan Jin; Emma Bowes; Krishnageetha Manoharan; David Maldonado-Perez; Clare Verill; Ian Humphreys; Tao Dong
Title: Low basal expression and slow induction of IFITM3 puts immune cells at risk of influenza A infection Document date: 2019_12_23
ID: ahs2wdus_47
Snippet: Separating this into individual cell types and comparing the fold change 459 in IFITM3 expression as compared to unstimulated samples, we found that 460 . CC-BY-NC-ND 4.0 International license author/funder. It is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2019.12.20.885590 doi: bioRxiv preprint CD14 + monocytes, CD1c + DC and pDC can induce more than 3-fold increas.....
Document: Separating this into individual cell types and comparing the fold change 459 in IFITM3 expression as compared to unstimulated samples, we found that 460 . CC-BY-NC-ND 4.0 International license author/funder. It is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2019.12.20.885590 doi: bioRxiv preprint CD14 + monocytes, CD1c + DC and pDC can induce more than 3-fold increase 461 in IFITM3 expression following Type I IFN stimulation (Figure 5e) . . NK and B 462 cells also increased expression of IFITM3 modestly following type I IFN 463
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