Selected article for: "cell antigen and protein protein"
Author: Michael M. Lutz; Megan P. Worth; Meleana M. Hinchman; John S. L. Parker; Emily D. Ledgerwood
Title: Mammalian orthoreovirus infection is enhanced in cells pre-treated with sodium arsenite
  • Document date: 2019_2_20
    • ID: cpfwzudq_1
    Snippet: initiation and inhibition of de novo protein synthesis [4] . In response to the inhibition of 93 translation initiation, stress granules (SG) form in the cytoplasm. SG assembly is 94 mediated by the RNA binding proteins T-cell antigen 1 (TIA-1), TIA-1 related protein 95 (TIAR) and the Ras-GAP SH3-binding protein 1 (G3BP1), and results in the 96 compartmentalization of translationally-stalled mRNA transcripts, RNA-binding proteins, 97 40S ribosome.....
    Document: initiation and inhibition of de novo protein synthesis [4] . In response to the inhibition of 93 translation initiation, stress granules (SG) form in the cytoplasm. SG assembly is 94 mediated by the RNA binding proteins T-cell antigen 1 (TIA-1), TIA-1 related protein 95 (TIAR) and the Ras-GAP SH3-binding protein 1 (G3BP1), and results in the 96 compartmentalization of translationally-stalled mRNA transcripts, RNA-binding proteins, 97 40S ribosomes, and translation initiation factors [10, 11] . SG are considered to be sites of 98 mRNA triage, protecting mRNA transcripts until a stress is alleviated and the cell returns 99 to homeostasis. 100

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