CoViD‐19 epidemic follows the “kinetics” of enzymes with cooperative substrate binding

Silverstein, Todd P.

The Hill equation, which models the cooperative ligand‐receptor binding equilibrium, turns out to be useful in modeling the progression of infectious disease outbreaks such as CoViD‐19. The equation fits well the data for total and daily case numbers, allows tentative predictions for the half‐point and end point of the epidemic, and presents a mathematical characterization of how social interventions “flatten the curve” of the disease progression.