Author: ENGIN, Ayse Basak; ENGIN, Evren Doruk; ENGIN, Atilla
Title: Current opinion in neurological manifestations of SARS-CoV-2 infection Cord-id: puh97gfj Document date: 2021_3_29
ID: puh97gfj
Snippet: Neurological symptoms occur in approximately one third of hospitalized patients with coronavirus disease 2019 (COVID-19). Among these symptoms, hypoxic encephalopathy develops in one-fifth of severe cases, while ischemic strokes due to thrombotic complications are common in one-third of COVID-19 intensive care patients. Brain involvement of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) is eventuated by several routes, including hematogenous spread, trans-synaptic entry through inf
Document: Neurological symptoms occur in approximately one third of hospitalized patients with coronavirus disease 2019 (COVID-19). Among these symptoms, hypoxic encephalopathy develops in one-fifth of severe cases, while ischemic strokes due to thrombotic complications are common in one-third of COVID-19 intensive care patients. Brain involvement of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) is eventuated by several routes, including hematogenous spread, trans-synaptic entry through infected neurons, olfactory nerve, ocular epithelium, vascular endothelium and impaired blood–brain barrier. Besides the high angiotensin converting enzyme-2 (ACE2) binding affinity, and FURIN preactivation, SARS-CoV-2 maintains efficient neuronal entry while evading immune surveillance by utilizing basigin, and neuropilin-1 receptors. However, the neurological manifestations and their pathogenic mechanisms are still debated in COVID-19 patients.
Search related documents:
Co phrase search for related documents- acetylcholine receptor and acute respiratory: 1, 2, 3, 4, 5, 6, 7, 8
- acetylcholine receptor and acute respiratory syndrome coronavirus: 1, 2, 3, 4, 5
- acetylcholine receptor and acute respiratory syndrome sars: 1, 2, 3, 4, 5
- acetylcholine receptor and ad disease: 1, 2
- acid receptor and acute respiratory: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47
- acid receptor and acute respiratory syndrome coronavirus: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32
- acid receptor and acute respiratory syndrome sars: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37
- acidic protein and acute respiratory: 1, 2, 3
- acidic protein and acute respiratory syndrome coronavirus: 1, 2, 3
- acidic protein and acute respiratory syndrome sars: 1, 2, 3
- acidic protein and ad disease: 1, 2, 3
- acute ischemic and ad disease: 1
- acute respiratory and ad disease: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
- acute respiratory and local cns inflammation: 1
- acute respiratory and long period: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60
- acute respiratory syndrome coronavirus and ad disease: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17
- acute respiratory syndrome coronavirus and local cns inflammation: 1
- acute respiratory syndrome coronavirus and long period: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41
- acute respiratory syndrome sars and ad disease: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15
Co phrase search for related documents, hyperlinks ordered by date