Selected article for: "antiviral therapy and severe case"
Author: Figlerowicz, Magdalena; Mania, Anna; Lubarski, Karol; Lewandowska, Zuzanna; Służewski, Wojciech; Derwich, Katarzyna; Wachowiak, Jacek; Mazur-Melewska, Katarzyna
Title: First case of convalescent plasma transfusion in a child with COVID-19-associated severe aplastic anemia
  • Cord-id: v3l33up6
  • Document date: 2020_7_1
    • ID: v3l33up6
    Snippet: We present the case of a six-year-old girl with severe COVID-19, in whom SARS-CoV-2 was successfully eliminated after convalescent plasma transfusion. Children show a variable clinical course of COVID-19, from asymptomatic to critical. In our patient, we diagnosed COVID-19-associated aplastic anemia with severe pancytopenia. The correlation between SARS-CoV-2 infection with aplastic anemia remains unclear. At the beginning of the disease, we used antiviral drugs and immune modulators as therapy
    Document: We present the case of a six-year-old girl with severe COVID-19, in whom SARS-CoV-2 was successfully eliminated after convalescent plasma transfusion. Children show a variable clinical course of COVID-19, from asymptomatic to critical. In our patient, we diagnosed COVID-19-associated aplastic anemia with severe pancytopenia. The correlation between SARS-CoV-2 infection with aplastic anemia remains unclear. At the beginning of the disease, we used antiviral drugs and immune modulators as therapy but without any positive results. After providing a transfusion of convalescent plasma, the elimination of SARS-CoV-2 was observed. We did not observe any adverse events of this treatment. The girl still has a diagnosis of aplastic anemia and requires specialist therapy.

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