Author: Chad N. Brocker; Donghwan Kim; Tisha Melia; Kritika Karri; Thomas J. Velenosi; Shogo Takahashi; Jessica A. Bonzo; David J. Waxman; Frank J. Gonzalez
Title: Long non-coding RNA Gm15441 attenuates hepatic inflammasome activation in response to metabolic stress Document date: 2019_6_20
ID: dt0b7jnu_13
Snippet: Three major ChIP-seq peaks indicating PPARA binding were seen upstream of Gm15441, and one major peak was seen in the promoter region of Txnip. Examination of genomic sequences upstream of Gm15441 using Genomatix MatInspector (Genomatix, Munchen, Germany) identified seven peroxisome proliferator response elements (PPREs) within six genomic regions, designated A to F, within 10 kilobase (kb) upstream of the Gm15441 transcriptional start site (TSS).....
Document: Three major ChIP-seq peaks indicating PPARA binding were seen upstream of Gm15441, and one major peak was seen in the promoter region of Txnip. Examination of genomic sequences upstream of Gm15441 using Genomatix MatInspector (Genomatix, Munchen, Germany) identified seven peroxisome proliferator response elements (PPREs) within six genomic regions, designated A to F, within 10 kilobase (kb) upstream of the Gm15441 transcriptional start site (TSS) (Figure 3B ).
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