Author: Dannielle Wellington; Zixi Yin; Liwei Zhang; Jessica Forbester; Kerry Kite; Henry Laurenson-Schafer; Shokouh Makvandi-Nejad; Boquan Jin; Emma Bowes; Krishnageetha Manoharan; David Maldonado-Perez; Clare Verill; Ian Humphreys; Tao Dong
Title: Low basal expression and slow induction of IFITM3 puts immune cells at risk of influenza A infection Document date: 2019_12_23
ID: ahs2wdus_73
Snippet: This delay in IFITM3 expression following IFN induction further increases the 571 risk of infection in cells with low IFITM3 basal expression, even if they can 572 then induce IFITM3 following IFN stimulation. This suggests that, in some 573 cases, IFITM3 is not a first line of defence against viral infection. 574.....
Document: This delay in IFITM3 expression following IFN induction further increases the 571 risk of infection in cells with low IFITM3 basal expression, even if they can 572 then induce IFITM3 following IFN stimulation. This suggests that, in some 573 cases, IFITM3 is not a first line of defence against viral infection. 574
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