A comparative multi-centre study on the clinical and imaging features of comfirmed and uncomfirmed patients with COVID-19

Congliang Miao; Jinqiang Zhuang; Mengdi Jin; Huanwen Xiong; Peng Huang; Qi Zhao; Li Miao; Jiang Du; Xinying Yang; Peijie Huang; Jiang Hong

Less common symptoms were diarrhea, headache, sore throat, upper airway congestion and a small number of severe patients developed chest tightness and dyspnea, indicating that the target cells might be located in the lower airway. This was consistent with the results of previous studies(7-10, 13-15). There were no significant differences in initial clinical symptoms between in Hubei province and outside Hubei province. These nonspecific symptoms are shared by winter respiratory diseases caused by bacteria and viruses, especially influenza. Influenza are usually characterized by fever, myalgia, headache and dry cough, most of which are self-limiting but may also progress to severe conditions, such as pneumonia, myocarditis and death (16, 17) . In addition, severe acute respiratory syndrome corona virus (SARS-CoV) and Middle East respiratory syndrome corona virus (MERS-CoV) also caused similar clinical symptoms, but more frequent diarrhea symptoms (18, 19) . To the best of our knowledge, this was the first multi-center study to compare the clinical features between confirmed group and unconfirmed group. All rights reserved. No reuse allowed without permission. the author/funder, who has granted medRxiv a license to display the preprint in perpetuity.