Author: Law, Carmella L. H.; Qassim, Mohammed; Cunningham, Anthony L.; Mulhall, Brian; Grierson, Jean M.
                    Title: Nonspecific Proctitis: Association with Human Immunodeficiency Virus Infection in Homosexual Men  Cord-id: xjtapifg  Document date: 1992_1_25
                    ID: xjtapifg
                    
                    Snippet: In a cross-sectional study of 140 homosexual men attending a sexually transmissible diseases clinic, the association between the presence of antibody to the human immunodeficiency virus (HIV) and the presence of proctitis, as determined by histologic examination, as well as past or present exposure to other pathogens and details of sexual practices was analyzed. Significant associations with HIV seropositivity were found with the number of lifetime partners, positive treponemal serology, and evi
                    
                    
                    
                     
                    
                    
                    
                    
                        
                            
                                Document: In a cross-sectional study of 140 homosexual men attending a sexually transmissible diseases clinic, the association between the presence of antibody to the human immunodeficiency virus (HIV) and the presence of proctitis, as determined by histologic examination, as well as past or present exposure to other pathogens and details of sexual practices was analyzed. Significant associations with HIV seropositivity were found with the number of lifetime partners, positive treponemal serology, and evidence of previous infection with herpes simplex virus. However the major and unique finding was the strong and independent association between proctitis diagnosed by histologic criteria and seropositivity for HIV. Whether this is cause or effect awaits further elucidation.
 
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