Author: Bingyi Yang; Justin Lessler; Huachen Zhu; Chaoqiang Jiang; Jonathan M. Read; James A Hay; Kin On Kwok; Ruiyin Shen; Yi Guan; Steven Riley; Derek A.T. Cummings
Title: Life course exposures continually shape antibody profile and risk of seroconversion to influenza Document date: 2020_1_16
ID: cyxn7dpw_162
Snippet: Indirect effect (path a path b): immune responses to previous strains have positive association between titer to strain i due to cross-reactions (path a), which has a negative association with seroconversion to strain i (path b). Direct effect (path c): effect of immune responses on seroconversion to strain i that was not mediated by titer to strain i. Total effect (path a path b + path c): combination of indirect effect and direct effect. Confou.....
Document: Indirect effect (path a path b): immune responses to previous strains have positive association between titer to strain i due to cross-reactions (path a), which has a negative association with seroconversion to strain i (path b). Direct effect (path c): effect of immune responses on seroconversion to strain i that was not mediated by titer to strain i. Total effect (path a path b + path c): combination of indirect effect and direct effect. Confounding effect (path d, e and f).
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