Author: Huijie Bian; Zhao-Hui Zheng; Ding Wei; Zheng Zhang; Wen-Zhen Kang; Chun-Qiu Hao; Ke Dong; Wen Kang; Jie-Lai Xia; Jin-Lin Miao; Rong-Hua Xie; Bin Wang; Xiu-Xuan Sun; Xiang-Min Yang; Peng Lin; Jie-Jie Geng; Ke Wang; Hong-Yong Cui; Kui Zhang; Xiao-Chun Chen; Hao Tang; Hong Du; Na Yao; Shuang-Shuang Liu; Lin-Na Liu; Zhe Zhang; Zhao-Wei Gao; Gang Nan; Qing-Yi Wang; Jian-Qi Lian; Zhi-Nan Chen; Ping Zhu
Title: Meplazumab treats COVID-19 pneumonia: an open-labelled, concurrent controlled add-on clinical trial Document date: 2020_3_24
ID: 6g34qwer_11
Snippet: Case severity of COVID-19 is categorized as common, severe, and critical by the vital signs, oxygenation index (PaO2/FiO2), chest radiographic, and vital organ function based on the Diagnosis and Treatment for 2019 Novel Coronavirus Disease. 18 Common case was featured by fever, respiratory symptoms, and radiographic pneumonia. Severe case was characterized by any of the following signs: dyspnea, respiratory frequency ≥30/minute, blood oxygen s.....
Document: Case severity of COVID-19 is categorized as common, severe, and critical by the vital signs, oxygenation index (PaO2/FiO2), chest radiographic, and vital organ function based on the Diagnosis and Treatment for 2019 Novel Coronavirus Disease. 18 Common case was featured by fever, respiratory symptoms, and radiographic pneumonia. Severe case was characterized by any of the following signs: dyspnea, respiratory frequency ≥30/minute, blood oxygen saturation ≤93%, and PaO2/FiO2 ratio <300mmHg. Critical case was characterized by any of the following signs: respiratory failure needing mechanical ventilation, shock, and multiple organ dysfunction/failure needing Intensive Care Unit (ICU). The patients who met all the following criteria will be discharged: body temperature recovered and remained normal more than 3 days; respiratory symptoms relief, and two continuous negative for nasopharyngeal swab test for SARS-CoV-2 (interval more than 24 hours).
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