Author: João Pedro Fonseca; Alain R. Bonny; G. Renuka Kumar; Andrew H. Ng; Jason Town; Qiu Chang Wu; Elham Aslankoohi; Susan Y. Chen; Patrick Harrigan; Lindsey C. Osimiri; Amy L. Kistler; Hana El-Samad
Title: A Toolkit for Rapid Modular Construction of Biological Circuits in Mammalian Cells Document date: 2018_12_26
ID: 1kugu5zk_38
Snippet: EBOV is encoded by ~19 kbp negative sense single stranded RNA genome that contains 3' non-coding regulatory leader (ldr) and 5' non-coding regulatory trailer (trl) sequences. These sequences flank a large central region that encodes seven distinct proteins (nucleoprotein, NP; 35 kDa phosphoprotein/polymerase co-factor, VP35; 40 kDa matrix protein, VP40; surface glycoprotein, GP; 30 kDa phosphoprotein/polymerase co-factor, VP35; 24 kDa regulatory .....
Document: EBOV is encoded by ~19 kbp negative sense single stranded RNA genome that contains 3' non-coding regulatory leader (ldr) and 5' non-coding regulatory trailer (trl) sequences. These sequences flank a large central region that encodes seven distinct proteins (nucleoprotein, NP; 35 kDa phosphoprotein/polymerase co-factor, VP35; 40 kDa matrix protein, VP40; surface glycoprotein, GP; 30 kDa phosphoprotein/polymerase co-factor, VP35; 24 kDa regulatory protein, VP24; and a large RNA dependent RNA polymerase protein, Lpol) (Fig. 7a ).
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