Selected article for: "actual case and case number"
Author: Gytis Dudas; Luiz Max Carvalho; Andrew Rambaut; Trevor Bedford; Ali M. Somily; Mazin Barry; Sarah S. Al Subaie; Abdulaziz A. BinSaeed; Fahad A. Alzamil; Waleed Zaher; Theeb Al Qahtani; Khaldoon Al Jerian; Scott J.N. McNabb; Imad A. Al-Jahdali; Ahmed M. Alotaibi; Nahid A. Batarfi; Matthew Cotten; Simon J. Watson; Spela Binter; Paul Kellam
Title: MERS-CoV spillover at the camel-human interface
  • Document date: 2017_8_10
    • ID: 8xcplab3_3
    Snippet: It is widely accepted that recorded human MERS-CoV infections are a result of at least several introductions of the virus into humans (Cotten et al., 2013) and that contact with camels is a major risk factor for developing MERS, per WHO guidelines (World Health Organization, 2016) . Previous studies attempting to quantify the actual number of spillover infections have either relied on case-based epidemiological approaches (Cauchemez et al., 2016).....
    Document: It is widely accepted that recorded human MERS-CoV infections are a result of at least several introductions of the virus into humans (Cotten et al., 2013) and that contact with camels is a major risk factor for developing MERS, per WHO guidelines (World Health Organization, 2016) . Previous studies attempting to quantify the actual number of spillover infections have either relied on case-based epidemiological approaches (Cauchemez et al., 2016) or employed methods agnostic to signals of population structure within sequence data (Zhang et al., 2016) . Here we use a dataset of 274 MERS-CoV genomes to investigate transmission patterns of the virus between humans and camels.

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