Author: Brito, Anderson F.; Semenova, Elizaveta; Dudas, Gytis; Hassler, Gabriel W.; Kalinich, Chaney C.; Kraemer, Moritz U.G.; Hill, Sarah C.; Sabino, Ester C.; Pybus, Oliver G.; Dye, Christopher; Bhatt, Samir; Flaxamn, Seth; Suchard, Marc A.; Grubaugh, Nathan D.; Baele, Guy; Faria, Nuno R.
Title: Global disparities in SARS-CoV-2 genomic surveillance Cord-id: hzniy7bi Document date: 2021_8_26
ID: hzniy7bi
Snippet: The COVID-19 pandemic has revealed the importance of virus genome sequencing to guide public health interventions to control virus transmission and understand SARS-CoV-2 evolution. As of July 20th, 2021, >2 million SARS-CoV-2 genomes have been submitted to GISAID, 94% from high income and 6% from low and middle income countries. Here, we analyse the spatial and temporal heterogeneity in SARS-CoV-2 global genomic surveillance efforts. We report a comprehensive analysis of virus lineage diversity
Document: The COVID-19 pandemic has revealed the importance of virus genome sequencing to guide public health interventions to control virus transmission and understand SARS-CoV-2 evolution. As of July 20th, 2021, >2 million SARS-CoV-2 genomes have been submitted to GISAID, 94% from high income and 6% from low and middle income countries. Here, we analyse the spatial and temporal heterogeneity in SARS-CoV-2 global genomic surveillance efforts. We report a comprehensive analysis of virus lineage diversity and genomic surveillance strategies adopted globally, and investigate their impact on the detection of known SARS-CoV-2 virus lineages and variants of concern. Our study provides a perspective on the global disparities surrounding SARS-CoV-2 genomic surveillance, their causes and consequences, and possible solutions to maximize the impact of pathogen genome sequencing for efforts on public health.
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