Author: Tutuncuoglu, Beril; Cakir, Merve; Batra, Jyoti; Bouhaddou, Mehdi; Eckhardt, Manon; Gordon, David E.; Krogan, Nevan J.
Title: The Landscape of Human Cancer Proteins Targeted by SARS-CoV-2 Cord-id: uuy94dwa Document date: 2020_5_22
ID: uuy94dwa
Snippet: The mapping of SARS-CoV-2 human protein–protein interactions by Gordon and colleagues revealed druggable targets that are hijacked by the virus. Here, we highlight several oncogenic pathways identified at the host–virus interface of SARS-CoV-2 to enable cancer biologists to apply their knowledge for rapid drug repurposing to treat COVID-19, and help inform the response to potential long-term complications of the disease.
Document: The mapping of SARS-CoV-2 human protein–protein interactions by Gordon and colleagues revealed druggable targets that are hijacked by the virus. Here, we highlight several oncogenic pathways identified at the host–virus interface of SARS-CoV-2 to enable cancer biologists to apply their knowledge for rapid drug repurposing to treat COVID-19, and help inform the response to potential long-term complications of the disease.
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