Selected article for: "acute liver injury and liver injury marker"

Author: Chad N. Brocker; Donghwan Kim; Tisha Melia; Kritika Karri; Thomas J. Velenosi; Shogo Takahashi; Jessica A. Bonzo; David J. Waxman; Frank J. Gonzalez
Title: Long non-coding RNA Gm15441 attenuates hepatic inflammasome activation in response to metabolic stress
  • Document date: 2019_6_20
  • ID: dt0b7jnu_32
    Snippet: APOA4 was stimulated by inflammation through activation of TNFR2 and NF-kB signaling in kidney tubular cells (Lee et al., 2017) . BHMT remethylates homocysteine to methionine using betaine and contributes to methionine, homocysteine, S-adenosylmethionine, and glutathione homeostasis (Perez-Miguelsanz et al., 2017) . In hepatocytes, BHMT upregulation prevent ER stress response, lipid accumulation, and cell death (Ji et al., 2007; Ji et al., 2008) .....
    Document: APOA4 was stimulated by inflammation through activation of TNFR2 and NF-kB signaling in kidney tubular cells (Lee et al., 2017) . BHMT remethylates homocysteine to methionine using betaine and contributes to methionine, homocysteine, S-adenosylmethionine, and glutathione homeostasis (Perez-Miguelsanz et al., 2017) . In hepatocytes, BHMT upregulation prevent ER stress response, lipid accumulation, and cell death (Ji et al., 2007; Ji et al., 2008) . Additionally, BHMT was identified as blood marker for acute liver injury and tumoral liver (Ma et al., 2014) .

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