Epidemiological investigation and intergenerational clinical characteristics of 24 COVID-19 patients associated with supermarket cluster

Suochen Tian; Min Wu; Zhenqin Chang; Yunxia Wang; Guijie Zhou; Wenming Zhang; Junmin Xing; Hui Tian; Xihong Zhang; Xiuli Zou; Lina Zhang; Mingxin Liu; Juan Chen; Jian Han; Kang Ning; Shuangfeng Chen; Tiejun Wu

The copyright holder for this preprint (which was not peer-reviewed) is . https://doi.org/10.1101/2020.04.11.20058891 doi: medRxiv preprint organ dysfunction syndrome (MODS) were severe or critical. 23 of the 24 patients in this group were moderate. However, according to the pneumonia severity index (PSI) score, 83.3%(16+4/24) of the patients were mild patients of grade I and II, 4 patients of grade III and IV did not develop severe or critical disease, and 1 patient of grade II, aged, with a history of diabetes, developed severe disease due to ARDS on the 20 days after the diagnosis of COVID 19. Admission symptoms, in addition to asymptomatic infection patients, the most common symptom was cough, followed by fever, and were low fever, other symptoms were successively shortness of breath, sore throat, gastrointestinal symptoms, fatigue. On the biochemical examination of admission, in addition to the white blood cell and lymphocyte counts, there were some changes beyond the normal range, but the absolute value of the change was not significant. It was important to note that all patients were admitted with chest CT scans showing pneumonia, often with bilateral infiltrations, including 7 asymptomatic patients. In terms of treatment during hospitalization, all patients were given 2-3 antiviral drugs, and some patients were given antibiotics, hormones and immunomodulators. Except for 1 case of severe COVID-19 was treated with High-Flow Nasal Cannula(HFNC), all the others were normal oxygen therapy. The application proportion of Traditional Chinese Medicine (TCM) was 100%, including Chinese medicine preparation, acupuncture, moxibustion, etc. (Table I, Table II) .