Selected article for: "direct evidence and low certainty"
Author: Francisca Verdugo-Paiva; Ariel Izcovich; Martin Ragusa; Gabriel Rada
Title: Lopinavir/ritonavir f?or the treatment of COVID-19: A living systematic review protocol
  • Document date: 2020_4_17
    • ID: mhi6w4mr_25
    Snippet: Types of studies We will preferentially include randomised trials. However, information from non-randomised studies will be used if there is no direct evidence from randomised trials or the certainty of evidence for the critical outcomes resulting from the randomised trials is graded as low-or very low, and the certainty provided by the non-randomised evidence grades higher than the one provided by the randomised evidence [ 22 ] . Studies evaluat.....
    Document: Types of studies We will preferentially include randomised trials. However, information from non-randomised studies will be used if there is no direct evidence from randomised trials or the certainty of evidence for the critical outcomes resulting from the randomised trials is graded as low-or very low, and the certainty provided by the non-randomised evidence grades higher than the one provided by the randomised evidence [ 22 ] . Studies evaluating the effects on animal models or in vitro conditions will be excluded.

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