Author: Dannielle Wellington; Zixi Yin; Liwei Zhang; Jessica Forbester; Kerry Kite; Henry Laurenson-Schafer; Shokouh Makvandi-Nejad; Boquan Jin; Emma Bowes; Krishnageetha Manoharan; David Maldonado-Perez; Clare Verill; Ian Humphreys; Tao Dong
Title: Low basal expression and slow induction of IFITM3 puts immune cells at risk of influenza A infection Document date: 2019_12_23
ID: ahs2wdus_28
Snippet: To determine whether cell origin affects IFITM3 basal expression, cell 323 subsets were grouped according to their lineage (Figure 1c) . For adult blood 324 there was significantly higher basal IFITM3 expression in myeloid cells 325 compared to lymphoid cells (p=0.0235). This higher expression in myeloid 326 cells compared to lymphoid was replicated in lung tissue samples (p<0.0001). 327.....
Document: To determine whether cell origin affects IFITM3 basal expression, cell 323 subsets were grouped according to their lineage (Figure 1c) . For adult blood 324 there was significantly higher basal IFITM3 expression in myeloid cells 325 compared to lymphoid cells (p=0.0235). This higher expression in myeloid 326 cells compared to lymphoid was replicated in lung tissue samples (p<0.0001). 327
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