Key Points of Clinical and CT Imaging Features of 2019 Novel Coronavirus (2019-nCoV) Imported Pneumonia Based On 21 Cases Analysis

wenxiu Wu; zhifeng xu; yabin Jin; aizhen Pan

Due to the large and complex population movements, the diversity of transmission pathways [5, 8, 9] (droplets,contact, fecal-oral and aerosol pathways),and natural and intermediate hosts are not fully understood, this leads to ambiguous contact history information. In addition, some patients do not have typical symptoms of fever and cough, and there may be basic lesions or complex infections that lead to the lack of changes in the number of typical white blood cells and lymphocytes, which all increase the difficulty of clinical diagnosis. At present, nucleic acid detection was still as gold standard to confirmed NCP, but the sensitivity and specificity of NCP was not evaluated [10] .According to current clinical observation, the positive rate is only 30%-50%. It has been found that patients with high clinical suspicion still have negative viral nucleic acid test for 2 times, while chest CT has displayed obvious lesions [11] . Unlucky, at the beginning, these patients failed to timely and effectively prevent and control due to negative nucleic acid test, leading to the expansion of the infection. CT diagnosis specificity is not as good as nucleic acid, but its sensitivity is significantly higher than nucleic acid. Therefore, to fight the epidemic front in Wuhan, doctor Zhang urgently called for " NPC diagnosis should not blindly believe in nucleic acid testing, chest CT findings should take as the main diagnostic basis". Therefore, the fifth edition of NCP diagnostic All rights reserved. No reuse allowed without permission. the author/funder, who has granted medRxiv a license to display the preprint in perpetuity.