Author: Qifang Bi; Yongsheng Wu; Shujiang Mei; Chenfei Ye; Xuan Zou; Zhen Zhang; Xiaojian Liu; Lan Wei; Shaun A Truelove; Tong Zhang; Wei Gao; Cong Cheng; Xiujuan Tang; Xiaoliang Wu; Yu Wu; Binbin Sun; Suli Huang; Yu Sun; Juncen Zhang; Ting Ma; Justin Lessler; Teijian Feng
Title: Epidemiology and Transmission of COVID-19 in Shenzhen China: Analysis of 391 cases and 1,286 of their close contacts Document date: 2020_3_4
ID: hnx213kp_44
Snippet: Focusing on cases detected through contact-based surveillance adds nuance to previous characterizations of COVID-19. Since PCR testing of contacts is near universal, we can assume these cases are more reflective of the average SARS-CoV-2 infection than cases detected through symptomatic surveillance. In the contact-based surveillance group, any tendency for cases to be male or older (beyond the underlying population distribution, see Table S3 ) d.....
Document: Focusing on cases detected through contact-based surveillance adds nuance to previous characterizations of COVID-19. Since PCR testing of contacts is near universal, we can assume these cases are more reflective of the average SARS-CoV-2 infection than cases detected through symptomatic surveillance. In the contact-based surveillance group, any tendency for cases to be male or older (beyond the underlying population distribution, see Table S3 ) disappears. Further, in this group, 20% were asymptomatic at the time of first clinical assessment and nearly 30% did not have fever. This is consistent with a reasonably high rate of asymptomatic carriage, but less than suggested by some modeling studies 18 , though PCR has imperfect sensitivity 20 .
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