Author: Tallmadge, R L; Brindley, M A; Salmans, J; Mealey, R H; Maury, W; Carpenter, S
Title: Development and characterization of an equine infectious anemia virus Env-pseudotyped reporter virus. Cord-id: fqqbyqnh Document date: 2008_1_1
ID: fqqbyqnh
Snippet: We developed a replication-defective reporter virus pseudotyped with the envelope glycoprotein of equine infectious anemia virus (EIAV). The in vitro host range and neutralization phenotype of EIAV Env-pseudotyped virus were similar to those of replication-competent virus. An EIAV Env pseudovirus will improve antigenic characterization of viral variants and evaluation of lentivirus vaccines.
Document: We developed a replication-defective reporter virus pseudotyped with the envelope glycoprotein of equine infectious anemia virus (EIAV). The in vitro host range and neutralization phenotype of EIAV Env-pseudotyped virus were similar to those of replication-competent virus. An EIAV Env pseudovirus will improve antigenic characterization of viral variants and evaluation of lentivirus vaccines.
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