Selected article for: "heat shock and protein expression"
Author: Michael M. Lutz; Megan P. Worth; Meleana M. Hinchman; John S. L. Parker; Emily D. Ledgerwood
Title: Mammalian orthoreovirus infection is enhanced in cells pre-treated with sodium arsenite
  • Document date: 2019_2_20
    • ID: cpfwzudq_35
    Snippet: Pre-treatment of cells with SA led to enhanced viral protein expression, increased 430 infectivity, and higher viral titers. Given that reovirus compartmentalizes the translational 431 machinery in VF and that components of the translational machinery are also sequestered 432 within SGs, we previously speculated that SGs may serve as a reservoir of translational 433 machinery for reovirus VFs [23] . However, comparison of reovirus infection follo.....
    Document: Pre-treatment of cells with SA led to enhanced viral protein expression, increased 430 infectivity, and higher viral titers. Given that reovirus compartmentalizes the translational 431 machinery in VF and that components of the translational machinery are also sequestered 432 within SGs, we previously speculated that SGs may serve as a reservoir of translational 433 machinery for reovirus VFs [23] . However, comparison of reovirus infection following 434 pre-treatment with either SA or heat shock (HS) suggests that the benefit is independent 435 of SG formation, as both treatments resulted in a robust induction of SGs, but only SA 436 All rights reserved. No reuse allowed without permission.

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